UNITED STATES PATENT:
Non-Toxic Skin Cancer Therapy
with Copper Peptides (2017)
GHK and DNA: Resetting the
Human Genome to Health
BioMed Research International (2014)
The Effect of Human Peptide
GHK Relevant to
Nervous System Function
and Cognitive Decline
Brain Sciences (2017)
Tri-Peptide GHK-Cu and
Acute Lung Injury in Mice
Oncotarget (2016)
New Data of the Cosmeceutical
and TriPeptide GHK
SOFW Journal (2015)
Biomarkers Reveal Potential
Skin Toxicity Caused by
Certain Copper Compounds
Scientific Reports (2016)

GHK-Cu May Prevent
Oxidative Stress in Skin
by Regulating Copper and
Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Induces
Programmed Cell Death
in Neuroblastoma Cells
Biotech & Biomaterials (2012)
GHK Peptide as a
Natural Modulator of
Multiple Cellular Pathways
in Skin Regeneration (2015)
Emphysema-Related
Lung Destruction and
its Reversal by GHK
Genome Medicine (2012)
GHK:
The Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology (2014)
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Biological Actions Similarities of GHK-Copper and Copper Salicylates

GHK has many diverse biological actions, an effect which unfortunately makes acceptance of its biological role by many researchers difficult. However, there is another copper-binding molecule with surprisingly similar actions to GHK-Copper.

The late John R. J. Sorenson (University of Arkansas) developed many salicylate-copper complexes that possess potentially therapeutic actions. The most active of these was diisipropylsalicylate-copper.

Comparison of GHK-copper and copper salicylate actions
Action GHK-copper Diisopropylsalicylate-copper
Wound healing Yes Yes
Inhibit cancer growth Yes Yes
Anti-ulcer Yes Yes
Anti-pain (Analgesic) Yes Yes
Anti-inflammatory Yes Yes
Improve recovery after radiation Yes Yes
Increase stem cells Yes Yes

 

Antiinflammatory, analgesic, and antiulcer activities of copper complexes suggest their use in a physiologic approach to treatment of arthritic diseases. Sorenson JR. Basic Life Sci. 1988;49:591-4. No abstract available

Prog Med Chem. 1989;26:437-568. Copper complexes offer a physiological approach to treatment of chronic diseases. Sorenson JR.

Exp Hematol. 1990 Aug;18(7):801-5. Postirradiation treatment with copper(II)2(3,5-diisopropylsalicylate)4 enhances radiation recovery and hemopoietic regeneration. Soderberg LS1, Barnett JB, Baker ML, Salari H, Sorenson JR.

Radiation protection and radiation recovery with essential metalloelement chelates. Sorenson JR, Soderberg LS, Chang LW. Proc Soc Exp Biol Med. 1995 Dec;210(3):191-204. Review. PMID: 8539256 [PubMed - indexed for MEDLINE]

Exp Hematol. 1988 Aug;16(7):577-80. Copper(II)2(3,5-diisopropylsalicylate)4 stimulates hemopoiesis in normal and irradiated mice. Soderberg LS1, Barnett JB, Baker ML, Chang LW, Salari H, Sorenson JR.

Adv Exp Med Biol. 1989;258:229-34. Bioavailable copper complexes offer a physiologic approach to treatment of chronic diseases. Sorenson JR1, Soderberg LS, Chidambaram MV, de la Rosa DT, Salari H, Bond K, Kearns GL, Gray RA, Epperson CE, Baker ML.

 

CopperTransport_AlbuminDIPS


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