New Data of the Cosmeceutical and TriPeptide GHK
SOFW Journal (2015)
GHK-Cu May Prevent Oxidative Stress in Skin
by Regulating Copper and Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Peptide as a Natural Modulator of
Multiple Cellular Pathways in Skin Regeneration (2015)
GHK, the Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology (2014)
GHK and DNA: Resetting the Human Genome to Health
BioMed Research International (2014)
Avoid Buying Fake Copper Peptides Dangerous


Skin and Hair Transplantation

GHK-Cu improved the transplants of skin grafts in pigs, mice, and humans.  For pig skin grafts, the best results were obtained by using GHK-Cu dissolved in a small amount of DMSO (dimethylsulfoxide). Normally in skin grafts, most of the grafted skin dies off, and  new skin grows outward from the surviving core of the skin graft. However, the addition of DMSO often so improved the graft "take" that the final graft "take" area exceeded the actual size of the skin graft.

 
Study Result Reference
Improvement of skin grafts in pigs

Click Photograph to Enlarge:
Left - Control Graft about 20% of skin graft (at center) established - this is a typical graft "take".

Right - Graft soaked in GHK-Cu in DMSO (dimethylsulfoxide).
Original graft overgrew transplant area.

 GHK Skin Transplant

Pickart  US Patent 4,760,051   Compositions containing glycyl-1-histidyl-1-lysine copper(II) enhance the wound healing process without evoking an antigenic response. 





















Tested GHK-Cu on skin transplants in mice Transplanted 1.5 cm diameter full thickness skin grafts in mice. This is considered an "impossible" transplant experiment 40% of full thickness transplants became permanent grafts  Pickart  Iamin: A Human Growth Factor with Multiple Wound Healing Properties. in  Biology of Copper Complexes, Clifton, NJ, 1987, pp. 273-285.
Human hair transplants  Studied the effect of GHK-Cu analog on hair transplants. Treated patients saw new hair growth in six weeks, versus the normal 10 to 14 weeks. In most cases, skin crusting after transplantation is reduced from 10 to 14 days to five days. Increased the degree of hair outgrowth from human hair transplants  Perez-Meza et al, (International Journal of Cosmetic Surgery (Vol. 6, 1998, pp 80-84)
Human hair transplants  30 hair transplant patients, found GHK-Cu analog reduced the shedding of transplanted hair from 30 percent with saline to 10 percent. The healing time of the transplanted grafts was cut in half. Regrowth of new hair from the transplants occurred in six to eight weeks with saline and four to six weeks with GHK-CU analog. Patient satisfaction after transplantation rose from 80 percent to 95 percent. Hitzig,G. Enhanced healing and growth in hair transplantation using copper peptides, Cosmetic Dermatol 2000 (June) ; 13, 18-21

Questions or Advice?

Email Dr. Loren Pickart: drlorenpickart@gmail.com

Alternate Email: ghkcopperpeptides@gmail.com

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