Search Skin Biology


NEW RELEASE:
GHK Enhances
Mesenchymal Stem Cells
Osteogenesis
Acta Biomaterialia (2019)
Self-Assembled
Antibacterial GHK-Cu
Nanoparticles for
Wound Healing
Particle & Particle (2019)
Effect of GHK-Cu
on Stem Cells and
Relevant Genes
OBM Geriatrics
(2018)
GHK Alleviates
Neuronal Apoptosis Due
to Brain Hemorrhage
Frontiers in Neuroscience
(2018)
GHK-Cu:
Endogenous Antioxidant
International Journal of Pathophysiology and Pharmacology (2018)
Regenerative and
Protective Actions of
GHK-Cu Peptide
International Journal of
Molecular Sciences
(2018)
Skin Regenerative and
Anti-Cancer Actions
of Copper Peptides
Cosmetics
(2018)
GHK-Cu Accelerates
Scald Wound Healing
Promoting Angiogenesis
Wound Repair and
Regeneration
(2017)

GHK Peptide Inhibits
Pulmonary Fibrosis
by Suppressing TGF-β1
Frontiers in Pharmacology
(2017)
UNITED STATES PATENT:
Non-Toxic
Skin Cancer Therapy
with Copper Peptides
(2017)
The Effect of Human
Peptide GHK Relevant to
Nervous System Function
and Cognitive Decline
Brain Sciences (2017)
Effects of Tripeptide
GHK in Pain-Induced
Aggressive Behavior
Bulletin of Experimental
Biology & Medicine
(2017)
GHK-Cu Elicits
In Vitro Alterations
in Extracellular Matrix
Am Journal of Respiratory
and Critical Care Medicine

(2017)
Selected Biomarkers &
Copper Compounds
Scientific Reports

(2016)
GHK-Cu on Collagen,
Elastin, and Facial Wrinkles
Journal of Aging Science
(2016)
Tri-Peptide GHK-Cu
and Acute Lung Injury
Oncotarget
(2016)

Effect of GHK Peptide
on Pain Sensitivity
Experimental
Pharmacology
(2015)

New Data of the
Cosmeceutical
and TriPeptide GHK
SOFW Journal
(2015)
GHK Peptide as a
Natural Modulator of
Multiple Cellular Pathways
in Skin Regeneration
BioMed Research (2015)
Resetting Skin Genome
Back to Health
Naturally with GHK
Textbook of Aging Skin
(2015)
GHK-Cu May Prevent
Oxidative Stress in Skin
by Regulating Copper and
Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Increases
TGF-β1 in
Human Fibroblasts

Acta Poloniae
Pharmaceutica

(2014)
GHK:
The Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology
(2014)
GHK & DNA:
Resetting the
Human Genome to Health
BioMed Research
International
(2014)
Enhanced Tropic Factor Secretion of Mesenchymal
Stem Cells with GHK
Acta Biomater
(2014)
Anxiolytic (Anti-Anxiety)
Effects of GHK Peptide
Bulletin of Experimental
Biology & Medicine
(2014)
Emphysema-Related
Lung Destruction and
its Reversal by GHK
Genome Medicine
(2012)
TriPeptide GHK Induces
Programmed Cell Death
of Neuroblastoma
Journal of Biotechnology
(2012)
Stem Cell
Recovering Effect
of GHK in Skin
Peptide Science
(2012)
Skin Penetration of
Copper Tripeptide in Vitro
Journal of International
Inflammation Research
(2010)
Possible Therapeutics
for Colorectal Cancer
Journal of Clinical and
Experimental Metastasis
(2010)
UNITED STATES PATENT:
Methods of Controlling
Differentiation and
Proliferation of Stem Cells
(2005)
Effects of
Copper Tripeptide
on Irradiated Fibroblasts
American Medical Association
(2005)
--- CLICK TO VIEW ALL ---
Avoid Buying Fake Copper Peptides Dangerous























































































Skin and Hair Transplantation

GHK-Cu improved the transplants of skin grafts in pigs, mice, and humans.  For pig skin grafts, the best results were obtained by using GHK-Cu dissolved in a small amount of DMSO (dimethylsulfoxide). Normally in skin grafts, most of the grafted skin dies off, and  new skin grows outward from the surviving core of the skin graft. However, the addition of DMSO often so improved the graft "take" that the final graft "take" area exceeded the actual size of the skin graft.

 
Study Result Reference
Improvement of skin grafts in pigs

Click Photograph to Enlarge:
Left - Control Graft about 20% of skin graft (at center) established - this is a typical graft "take".

Right - Graft soaked in GHK-Cu in DMSO (dimethylsulfoxide).
Original graft overgrew transplant area.

 GHK Skin Transplant

Pickart  US Patent 4,760,051   Compositions containing glycyl-1-histidyl-1-lysine copper(II) enhance the wound healing process without evoking an antigenic response. 





















Tested GHK-Cu on skin transplants in mice Transplanted 1.5 cm diameter full thickness skin grafts in mice. This is considered an "impossible" transplant experiment 40% of full thickness transplants became permanent grafts  Pickart  Iamin: A Human Growth Factor with Multiple Wound Healing Properties. in  Biology of Copper Complexes, Clifton, NJ, 1987, pp. 273-285.
Human hair transplants  Studied the effect of GHK-Cu analog on hair transplants. Treated patients saw new hair growth in six weeks, versus the normal 10 to 14 weeks. In most cases, skin crusting after transplantation is reduced from 10 to 14 days to five days. Increased the degree of hair outgrowth from human hair transplants  Perez-Meza et al, (International Journal of Cosmetic Surgery (Vol. 6, 1998, pp 80-84)
Human hair transplants  30 hair transplant patients, found GHK-Cu analog reduced the shedding of transplanted hair from 30 percent with saline to 10 percent. The healing time of the transplanted grafts was cut in half. Regrowth of new hair from the transplants occurred in six to eight weeks with saline and four to six weeks with GHK-CU analog. Patient satisfaction after transplantation rose from 80 percent to 95 percent. Hitzig,G. Enhanced healing and growth in hair transplantation using copper peptides, Cosmetic Dermatol 2000 (June) ; 13, 18-21

Questions or Advice?

Email Dr. Loren Pickart: drlorenpickart@gmail.com

Call us at 1-800-405-1912 Monday through Friday (8 am to 6 pm) PST